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Antibacterial activity of lipo-α/sulfono-γ-AA hybrid peptides

https://doi.org/10.1016/j.ejmech.2019.111901

Wei, Lulu ; Wang, Minghui ; Gao, Ruixuan ; Fatirkhorani, Rojin ; Cai, Jianfeng ( January 2020 , European Journal of Medicinal Chemistry)

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Lipidated α/Sulfono-α-AA heterogeneous peptides as antimicrobial agents for MRSA

https://doi.org/10.1016/j.bmc.2019.115241

Singh, Sylvia ; Wang, Minghui ; Gao, Ruixuan ; Teng, Peng ; Odom, Timothy ; Zhang, En ; Xu, Hai ; Cai, Jianfeng ( January 2020 , Bioorganic & Medicinal Chemistry)

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The Activity of Small Urea‐γ‐AApeptides Toward Gram‐Positive Bacteria

https://doi.org/10.1002/cmdc.201900520

Su, Ma ; Shi, Yan ; Wang, Minghui ; Gao, Ruixuan ; Wu, Jianfeng ; Xu, Hai ; Xi, Chuanwu ; Cai, Jianfeng ( November 2019 , ChemMedChem)

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Polymyxin derivatives as broad-spectrum antibiotic agents

https://doi.org/10.1039/C9CC06908A

Su, Ma ; Wang, Minghui ; Hong, Yuzhu ; Nimmagadda, Alekhya ; Shen, Ning ; Shi, Yan ; Gao, Ruixuan ; Zhang, En ; Cao, Chuanhai ; Cai, Jianfeng ( October 2019 , Chemical Communications)

We designed a few polymyxin derivatives which exhibit broad-spectrum antimicrobial activity. Lead compound P1 could disrupt bacterial membranes rapidly without developing resistance, inhibit biofilms formed by E. coli , and exhibit excellent in vivo activity in an MRSA-infected thigh burden mouse model.
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Predicting Golgi-Resident Protein Types Using Conditional Covariance Minimization With XGBoost Based on Multiple Features Fusion

https://doi.org/10.1109/ACCESS.2019.2938081

Zhou, Hongyan ; Chen, Cheng ; Wang, Minghui ; Ma, Qin ; Yu, Bin ( January 2019 , IEEE Access)
Helical Sulfono-γ-AApeptides with Aggregation-Induced Emission and Circularly Polarized Luminescence

https://doi.org/10.1021/jacs.9b05329

Shi, Yan ; Yin, Guangqiang ; Yan, Zhiping ; Sang, Peng ; Wang, Minghui ; Brzozowski, Robert ; Eswara, Prahathees ; Wojtas, Lukasz ; Zheng, Youxuan ; Li, Xiaopeng ; et al ( July 2019 , Journal of the American Chemical Society)

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Lipidated α/α-AA heterogeneous peptides as antimicrobial agents

https://doi.org/10.1016/j.ejmech.2018.06.006

Singh, Sylvia ; Nimmagadda, Alekhya ; Su, Ma ; Wang, Minghui ; Teng, Peng ; Cai, Jianfeng ( July 2018 , European Journal of Medicinal Chemistry)

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Rational Design of Dimeric Lysine N -Alkylamides as Potent and Broad-Spectrum Antibacterial Agents

https://doi.org/10.1021/acs.jmedchem.7b01704

Niu, Youhong ; Wang, Minghui ; Cao, Yafei ; Nimmagadda, Alekhya ; Hu, Jianxing ; Wu, Yanfen ; Cai, Jianfeng ; Ye, Xin-Shan ( March 2018 , Journal of Medicinal Chemistry)

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The Number of Meiotic Double-Strand Breaks Influences Crossover Distribution in Arabidopsis

https://doi.org/10.1105/tpc.18.00531

Xue, Ming ; Wang, Jun ; Jiang, Luguang ; Wang, Minghui ; Wolfe, Sarah ; Pawlowski, Wojciech P. ; Wang, Yingxiang ; He, Yan ( October 2018 , The Plant Cell)
Genomic features shaping the landscape of meiotic double-strand-break hotspots in maize

https://doi.org/10.1073/pnas.1713225114

He, Yan ; Wang, Minghui ; Dukowic-Schulze, Stefanie ; Zhou, Adele ; Tiang, Choon-Lin ; Shilo, Shay ; Sidhu, Gaganpreet K. ; Eichten, Steven ; Bradbury, Peter ; Springer, Nathan M. ; et al ( November 2017 , Proceedings of the National Academy of Sciences)

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